Proteínas diseñadas por computadora se dirigen al receptor inmunitario vinculado a la inflamación en el nuevo sitio 'intoxicable'

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To sense their environment and respond accordingly, cells enlist membrane proteins as communication hubs, receiving molecular messages from outside and triggering responses inside. One of these proteins is Toll-like receptor 4 (TLR4), an immune receptor that plays an essential role in protecting against infections. But overactivity of TLR4 has been linked to inflammatory disorders like sepsis,…

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