COMPASS pathway enables regulatory T cells to prevent devastating autoimmune responses to gut bacteria

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Trillions of bacteria live in the human gut without triggering an immune response. Scientists at St. Jude Children's Research Hospital have now discovered a gene-regulatory pathway that helps maintain this delicate balance. In a study published in Science Advances, they show that regulatory T cells, a type of immune cell, co-opt a well-known general gene expression pathway called COMPASS to…

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